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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPTOR All Species: 25.15
Human Site: S898 Identified Species: 50.3
UniProt: Q8N122 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N122 NP_065812.1 1335 149038 S898 D V A K Q P V S R D L P S G R
Chimpanzee Pan troglodytes XP_001161716 1335 149161 S898 D V A K Q P V S R D L P S G R
Rhesus Macaque Macaca mulatta XP_001110471 1335 148870 S898 D V A K Q P V S R D L P S G R
Dog Lupus familis XP_850487 1335 149172 S898 D V A K Q P V S R D L P A G R
Cat Felis silvestris
Mouse Mus musculus Q8K4Q0 1335 149453 S898 D V A K Q T V S R D L P S S R
Rat Rattus norvegicus NP_001127971 1335 149475 S898 D V A K Q T V S R D L P S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426232 1335 149895 S898 D V T K Q P V S R D I T S V R
Frog Xenopus laevis NP_001088177 1334 149513 N896 D V T K P P V N R D I P S N R
Zebra Danio Brachydanio rerio XP_001919288 1332 149175 R898 E V P K P P V R D G P S A R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624060 1279 144157 V851 K G D S P P T V N S G T D L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323654 1366 149968 P923 D M N A G H L P F R T P P V S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38873 1557 177591 A1054 N E R V D N N A F K K E Q Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 95.9 N.A. 96.5 96.7 N.A. N.A. 95 90.5 87.9 N.A. N.A. 55.5 N.A. N.A.
Protein Similarity: 100 99.5 99.1 98.3 N.A. 98.4 98.5 N.A. N.A. 97.6 95.9 94.6 N.A. N.A. 70.4 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 73.3 66.6 26.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. 80 80 40 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: 40.8 N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: 58.2 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 9 0 0 0 9 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 75 0 9 0 9 0 0 0 9 67 0 0 9 0 0 % D
% Glu: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 0 0 0 9 9 0 0 34 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % I
% Lys: 9 0 0 75 0 0 0 0 0 9 9 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 50 0 0 9 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 9 9 9 9 0 0 0 0 9 0 % N
% Pro: 0 0 9 0 25 67 0 9 0 0 9 67 9 0 9 % P
% Gln: 0 0 0 0 59 0 0 0 0 0 0 0 9 9 9 % Q
% Arg: 0 0 9 0 0 0 0 9 67 9 0 0 0 9 67 % R
% Ser: 0 0 0 9 0 0 0 59 0 9 0 9 59 17 9 % S
% Thr: 0 0 17 0 0 17 9 0 0 0 9 17 0 0 0 % T
% Val: 0 75 0 9 0 0 75 9 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _